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Gene silencing predicted to improve drug manufacturing. The burgeoning science of RNA interference, touted as the next frontier in pharmaceutical treatment, is now being directed at increasing the efficiency of drug manufacturing processes. Nature. 21 November 2009.
Early life stress 'changes' genes. A study in mice has hinted at the impact that early life trauma and stress can have on genes, and how they can result in behavioural problems. Scientists described the long-term effects of stress on baby mice in the journal Nature Neuroscience. BBC. 10 November 2009.
Population: Technology will save us. Throughout history, technological innovation has saved us from being overwhelmed by overpopulation, and Jesse Ausubel tells Alison George why he is convinced that human resourcefulness can pull the fat out of the fire even now. New Scientist. Opinion, 27 September 2009.
Scientists can't replicate pioneering epigenetic results. The murky waters of the debate over chemical exposures and health just got murkier. And a bit nastier. Miller-McCune. Opinion, 26 September 2009.
Key environmental epigenetics paper challenged. The findings of a key paper with potentially profound implications for the future of environmental health research and regulation are being challenged by a small group of government and industry scientists who say they cannot replicate its results. Environmental Science & Technology. 24 September 2009.
Seeking chemical culprits for those deformities. Science is casting wide net in search of chemicals seen as likely suspects in feminization and reproductive anomalies being spotted worldwide. Miller-McCune. 23 September 2009.
Benefit and doubt in vaccine additive. Additives could stretch the supply of swine flu vaccine. But U.S. officials have doubts about the substances’ safety--and are worried about using an unproven vaccine to help protect people in other countries. New York Times. 22 September 2009. [Registration Required]
New findings about disorder in bees. Scientists in the United States and other countries have been working to explain the mysterious disappearances of bees. Now, a new study suggests that several viruses may act together. Voice of America. 15 September 2009.
Mapping the epigenome. Growing recognition of the importance of epigenetic processes in human development and disease has fueled an insatiable thirst for new technologies to detect epigenetic modifications on a genomewide, or “epigenomic,” scale. Chemical & Engineering News. 14 September 2009.
Fat reprograms genes linked to diabetes. A gene that helps muscle cells burn fat can be radically altered and switched off if the cells carrying it are exposed to fat. The finding suggests that the same process may occur when people eat too much fat-rich junk food, resulting in drastic changes to this "fat burning" gene. New Scientist. 8 September 2009.
Obesity surgery's benefits extend to next generation. Children born to women who have achieved drastic weight loss through stomach surgery are healthier than children born to severely obese moms, a new study shows. The findings suggest that obesity creates an unhealthy environment for a fetus that has ramifications later on, scientists report. Science News. 2 September 2009.
Researchers find a clue to honeybee deaths. Scientists from the University of Illinois at Urbana-Champaign have found a clue in the gut of honey bees that might help identify a deadly disorder that's killing off some of the world's most important pollinators. St. Louis Post-Dispatch, Missouri. 31 August 2009.
DNA clue to honey bee deaths. Scientists say that mass bee deaths may be caused by viruses that disrupt gene expression. The team analysed which genes were turned on and which were turned off in healthy bees and those from hives with colony collapse disorder (CCD). BBC. 25 August 2009.
Biologists napping while work militarized. As researchers discover more agents that alter mental states, the Chemical Weapons Convention needs modification to help ensure that the life sciences are not used for hostile purposes. Nature. Opinion, 25 August 2009.
Epigenetic determinism. The juxtaposition of promise and peril appears over and over in books and papers, but Edward McCabe and Linda McCabe actually offer a reasonable view of the true magnitude of each. Science. Opinion, 14 August 2009. [Subscription Required]
Chemicals can turn genes on and off; new tests needed, scientists say. Each of us starts life with a particular set of genes, 20,000 to 25,000 of them. Now scientists are amassing a growing body of evidence that pollutants and chemicals might be altering those genes—not by mutating them, but by sending subtle signals that silence them or switch them on at the wrong times. Last week a National Academies workshop examined the evidence and implications. Environmental Health News. 3 August 2009.
Tox21: New dimensions of toxicity testing. New tests using automated systems that assess how chemicals interact with cellular processes may generate more accurate assessments of risks to people than current approaches, largely dependent upon animals. But will it work, and will it be enough for safety assessments? Environmental Health Perspectives. 3 August 2009.
Lights, camera, infection. Mark Miller uses multiphoton microscopy to watch infections in living animals in real time. His experiments, and others like it, are not just gripping the audience behind the curtain--they are gripping a much broader audience of immunologists. Nature. 30 July 2009.
Preventing preemies. When a baby is born too soon, it's hard to imagine that the infant would do better anywhere else in the world than in America. And yet for all the technology and expense, roughly 30,000 American babies under age 1 die each year. What explains such dismal figures? Time Magazine. 29 July 2009.
Study links exposure to pollution with lower IQ. A new study published in the journal Pediatrics links mothers' exposure to high levels of environmental pollutants during pregnancy to a four-point drop in children's IQ scores by age 5. Time Magazine. 29 July 2009.
The herbicide atrazine lowers the production of androgen hormones in male rats by altering the genes responsible for making them. This is the first study to show that atrazine directly affects the genes responsible for hormone production in testicular cells. 27 July 2009. More...
Fears that swine flu can attack unborn. The H1N1 flu virus can damage the developing brains of unborn offspring, scientists have found. They discovered that the virus changes the workings of genes that control fetal brain growth and development. London Times, United Kingdom. 26 July 2009.
Prenatal exposure to urban pollutants lowers IQ. Prenatal exposure to common air pollutants known as polycyclic aromatic hydrocarbons (PAHs) has for the first time been strongly linked to decreased intelligence. PAHs are byproducts from burning organic material, and their primary source in cities is motor vehicle emissions. Chemistry World. 25 July 2009.
Cancer does discriminate. For years, researchers have known that race is a factor in cancer survival. Black women are less likely than whites to get breast cancer, for example, but much more likely to die from it. Science. 9 July 2009.
Bad breath. Tasteless. Invisible to the eye. Air contaminants less than a tenth the size of a pollen grain are nevertheless dangerous. Studies have implicated tiny airborne particles in the deaths of huge numbers of people each year — even where concentrations never exceed levels permitted by U.S. law. Science News. 4 July 2009.
Aging well starts in womb, as mom's choices affect whole life. Research into the "developmental origins of adult disease" suggests that a mom's healthy living may help her child avoid problems such as cancer, heart disease, depression and diabetes not just in childhood, but 50 years from now. USA Today. 3 July 2009.
Pitt chemist is developing a bright idea. Researchers have created a fluorescent marker to detect even minute levels of ozone, offering a potential means to signal ozone levels that can cause respiratory problems in people with asthma. Fluorescent markers for mercury and other metals already are in various stages of development and use. Pittsburgh Post-Gazette, Pennsylvania. 3 July 2009.
Schizophrenia may be linked to immune system. Three new genetic studies are providing some tantalizing hints about what causes schizophrenia. The studies found such changes in stretches of code involved in brain development, memory and the immune system. All Things Considered, NPR. 2 July 2009.
Next-generation risk assessment. The Environmental Protection Agency is strongly considering revamping how it performs chemical risk assessments. Many advocates for change say the current system for ensuring the safety of chemicals is broken and EPA needs to do something radical to fix it. Chemical & Engineering News. 22 June 2009.
Estrogen may reprogram prostate cancer gene in black men. Earlier studies have shown that black men face a higher risk of prostate cancer than white men. Black men also have higher average levels of estrogen than white men. Science News. 16 June 2009.
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